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N-Methyl-N-trimethylsilyltrifluoroacetamide activated III

for GC derivatization, LiChropur, activated with imidazole

Synonym(s):

N-Methyl-N-trimethylsilyltrifluoroacetamide imidazole mixture, MSTFA activated III

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About This Item

CAS Number:
Beilstein:
1941550
MDL number:
UNSPSC Code:
41115710
PubChem Substance ID:
NACRES:
NA.22

grade

for GC derivatization

Quality Level

quality

LiChropur

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.383

storage temp.

2-8°C

SMILES string

CN(C(=O)C(F)(F)F)[Si](C)(C)C

InChI

1S/C6H12F3NOSi/c1-10(12(2,3)4)5(11)6(7,8)9/h1-4H3

InChI key

MSPCIZMDDUQPGJ-UHFFFAOYSA-N

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Application

2,2,2-trifluoro-N-methyl-N-trimethylsilylacetamide (N-Methyl-N-trimethylsilyltrifluoroacetamide activated III) may be used for derivatization, in an experimental study conducted to perform determination of scopolamine in human serum, by capillary column gas chromatographic-ion trap tandem mass spectrometric.

Analysis Note

Derivatizing agent for the per(trimethylsilylation) of analytes for GC and GC-MS

Other Notes

Derivatizing agent for the per(trimethylsilylation) of analytes for GC and GC-MS

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

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Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

78.8 °F - closed cup - Solvent

Flash Point(C)

26 °C - closed cup - Solvent

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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W. Schanzer et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 687, 93-93 (1996)

Articles

Results of a study involving the ability few Fluka silylating reagents to form GC-MS-compatible trimethylsilylmethyl derivatives of NSAIDs

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