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Key Documents

03880

Sigma-Aldrich

Poly(ethyleneimine) solution

~50% in H2O

Synonym(s):

Ethyleneimine polymer solution, PEI

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About This Item

CAS Number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

form

liquid

Quality Level

mol wt

Mr 600,000-1,000,000

concentration

~50% in H2O

InChI

1S/C2H5N/c1-2-3-1/h3H,1-2H2

InChI key

NOWKCMXCCJGMRR-UHFFFAOYSA-N

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Application

PEI has a high affinity for various metal ions and can be used to fabricate nanofibrous affinity membranes for the removal of heavy metal ions in wastewater.

It can be used to prepare potential gene delivery carriers as it can buffer the acidic pH of the lysosome and protect the DNA from degradation.

PEIfunctionalized monoliths can be used to immobilize enzymes without alteringtheir activity.

Features and Benefits

  • Good biocompatibility
  • Flexible polymer chain
  • It can be easily modified or functionalized for specific features
  • High transfection efficiency

Other Notes

Crosslinked polyethylenimine is used as enzyme carrier

Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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J. Zemek et al.
Enzyme and Microbial Technology, 4, 233-233 (1982)
Michael Moldavan et al.
The European journal of neuroscience, 42(12), 3018-3032 (2015-09-24)
GABA is a principal neurotransmitter in the suprachiasmatic hypothalamic nucleus (SCN), the master circadian clock. Despite the importance of GABA and GABA uptake for functioning of the circadian pacemaker, the localization and expression of GABA transporters (GATs) in the SCN
Yuki Miura et al.
Nature biotechnology, 38(12), 1421-1430 (2020-12-05)
Cortico-striatal projections are critical components of forebrain circuitry that regulate motivated behaviors. To enable the study of the human cortico-striatal pathway and how its dysfunction leads to neuropsychiatric disease, we developed a method to convert human pluripotent stem cells into

Articles

Professor Yoshiki Katayama (Kyushu University, Japan) discusses recent advances in drug delivery systems and strategies that exploit the EPR effect, with a special focus on stimuli-responsive systems based on novel materials.

We present an article that discusses two applications in particular; first, using these layers as polyelectrolyte membranes to control permeability.

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