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00320188

(−)-α-Bisabolol

primary reference standard

Synonym(s):

(−)-6-Methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol, Levomenol

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About This Item

Empirical Formula (Hill Notation):
C15H26O
CAS Number:
23089-26-1
Molecular Weight:
222.37
EC Number:
208-205-9
MDL number:
MFCD03412455
UNSPSC Code:
85151701
PubChem Substance ID:
329747043
NACRES:
NA.24

grade

primary reference standard

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

HWI

storage temp.

−20°C

SMILES string

C\C(C)=C\CC[C@](C)(O)[C@H]1CCC(C)=CC1

InChI

1S/C15H26O/c1-12(2)6-5-11-15(4,16)14-9-7-13(3)8-10-14/h6-7,14,16H,5,8-11H2,1-4H3/t14-,15+/m1/s1

InChI key

RGZSQWQPBWRIAQ-CABCVRRESA-N

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General description

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Application

Reference Standard in the analysis of herbal medicinal products

Other Notes

This compound is commonly found in plants of the genus: angelica

Hazard Statements

H412

Precautionary Statements

P273 - P501

Hazard Classifications

Aquatic Chronic 3

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

289.4 °F - closed cup

Flash Point(C)

143 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
HWI02175-1
HWI02175
HWI00345-3
HWI00345-2
HWI00345-1

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Christine Tschiggerl et al.
Plant foods for human nutrition (Dordrecht, Netherlands), 67(2), 129-135 (2012-03-14)
Chamomile (German Chamomile, Matricaria recutita L., Asteraceae) is one of the most popular medicinal plants in use as an herbal tea for food purposes and in folk medicine. Qualitative and semi-quantitative analyses of the volatile fraction of chamomile herbal tea
Seyed Mehdi Razavi
Natural product research, 26(22), 2148-2151 (2011-11-26)
Prangos pabularia Lindl. (Apiaceae) is a widespread perennial herb distributed from Russia to Iran, Turkey, India, Central Asia and Caucasian. It has been used in folk medicine from ancient times as a diuretic agent and a treatment for leukoplakia, digestive
Seungbeom Kim et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 49(10), 2580-2585 (2011-07-21)
Although (-)-α-bisabolol, a natural monocyclic sesquiterpene alcohol, is often used as a cosmetic soothing supplement, little is known about its mechanisms of anti-inflammatory effects. Therefore, this study was designed to investigate anti-inflammatory effects of (-)-α-bisabolol and its mechanisms of action.
Rodrigo J B de Siqueira et al.
Canadian journal of physiology and pharmacology, 90(1), 23-35 (2011-12-17)
The present study deals with the pharmacological effects of the sesquiterpene alcohol (-)-α-bisabolol on various smooth-muscle preparations from rats. Under resting tonus, (-)-α-bisabolol (30-300 µmol/L) relaxed duodenal strips, whereas it showed biphasic effects in other preparations, contracting endothelium-intact aortic rings and
Massimiliano Bonifacio et al.
PloS one, 7(10), e46674-e46674 (2012-10-12)
We showed that α-bisabolol is active against primary acute leukemia cells, including BCR-ABL(+) acute lymphoblastic leukemias (ALL). Here we studied the activity of α-bisabolol against BCR-ABL(+) cells using 3 cell lines (K562, LAMA-84, CML-T1) and 10 primary BCR-ABL(+) ALL samples.
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