PYR0MATCELLS
PyroMAT® cells
Cryopreserved MonoMac 6 cells for use in the Monocyte Activation Test (MAT) for Pyrogen testing, pkg of 2 vials
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About This Item
UNSPSC Code:
41116129
eCl@ss:
32160606
NACRES:
NA.74
Recommended Products
Agency
EP Chapter 2.6.30
Quality Level
feature
ready-to-use
packaging
pkg of 2 vials
manufacturer/tradename
PyroMAT®
application(s)
pharmaceutical
pyrogen testing
compatibility
configured for PyroMAT® System
shipped in
dry ice
suitability
pyrogenic bacteria
General description
The PYROMAT® system is a robust, easy-to-perform and ready-to-use solution for pyrogen testing, using the Monocyte Activation Test (MAT). The PYROMAT® cells are cryopreserved human monocytic cells from the Mono-Mac-6 cell line. They have been validated to be used for MAT.
The PyroMAT® System is based on the Mono-Mac-6 (MM6) cell line and uses Interleukin-6 (IL-6) as a read out.
PyroMATcells contains the crypreserved MonoMac 6 cells, 2 x 1 mL
PyroMATcells contains the crypreserved MonoMac 6 cells, 2 x 1 mL
Application
PYROMAT® cells is used to determine the pyrogenic activity in a solution or suspension by inducing interleukin production in cell cultures with human monocytes. It is used to ensure the safety of parenteral pharmaceutical products and medical devices.
Features and Benefits
- Cryopreserved ready-to-use monocytic cells
- The only cell line validated and available for the Monocyte Activation Test
- Expression of all the Toll-like Receptors responsible for pyrogen detection
Packaging
1 box of 2 vials, sufficient for 1 test
Components
2 vials of cryopreserved Mono-Mac-6 cells
Recommended products
To be used with PyroMAT kit (PYR0MATKIT), Reference standard endotoxin (144.161.0001), NEP controls (MATHKSA, MATFLAGELLIN)
Legal Information
PYROMAT is a registered trademark of Merck KGaA, Darmstadt, Germany
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Sens. 1
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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