MABN738

Anti-OCT6 Antibody, clone KT110

clone KT110, from mouse

• Synonym(s): POU domain, class 3, transcription factor 1, Octamer-binding protein 6, Oct-6, Octamer-binding transcription factor 6, OTF-6, POU domain transcription factor SCIP
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: KT110, monoclonal
• species reactivity: mouse, human
• technique(s): electrophoretic mobility shift assay: suitable; immunohistochemistry: suitable; western blot: suitable
• isotype: IgG1κ
• NCBI accession no.: NP_035271
• UniProt accession no.: P21952
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... SLC22A16(85413)

Description

General description

Octamer-binding protein 6 (Oct-6) is also called POU domain, class 3, transcription factor 1 (Pou3f1), Octamer-binding transcription factor 6 (OTF-6) and POU domain transcription factor SCIP. Oct-6 is a transcription factor that specifically binds to the (5′-ATTTGCAT-3′) octamer motif. Oct-6 has been implicated in early embryogenesis, neurogenesis, keratinocyte differentiation and myelination in the peripheral nervous system.

Immunogen

Recombinant protein corresponding to mouse OCT6.

Application

Anti-OCT6 Antibody, clone KT110 is a highly specific mouse monoclonal antibody, that targets Oct-6 & has been tested in western blotting, IHC & Electrophoretic Mobility Shift Assay.

Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected OCT6 in mouse embryonic brain (D15.5) tissue.
Electophoretic Mobility Shift Assay (EMSA) Analysis: A representative lot detected SphK1 in nuclear extracts from RT4 Schwannoma or primay rat Shcwann cells (Prof. D. Meijer, Erasmus University Medical Center, Rotterdam.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

Quality

Evaluated by Western Blotting in H9 human embreyonic stem cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected OCT6 in 10 µg of H9 human embreyonic stem cell lysate.

Target description

~50 kDa observed

Linkage

Replaces: MABN1060

Physical form

Format: Purified

Protein A purified

Purified mouse monoclonal IgG1κ in buffer containing PBS and 0.9% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable