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Key Documents

MABD83

Sigma-Aldrich

Anti-SOX10, clone 12H6.1 Antibody

clone 12H6.1, from mouse

Synonym(s):

SOX-10

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

12H6.1, monoclonal

species reactivity

human

technique(s)

western blot: suitable

isotype

IgG1κ

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... SOX10(6663)

General description

Transcription factor SOX10 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. Sox10 acts as a nucleocytoplasmic shuttle protein and is important for neural crest, glial and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.

Immunogen

KLH-conjugated linear peptide corresponding to Human SOX10.

Application

Detect SOX10 using this Anti-SOX10 antibody, clone 12H6.1 validated for use in western blotting.
Research Category
Stem Cell Research

Neuroscience
Research Sub Category
Developmental Neuroscience

Neurodegenerative Diseases

Quality

Evaluated by Western Blot in a SK-MEL-28 cell lysate. Western Blot Analysis: A 1:2000 dilution of this antibody detected SOX10 in a 10 µg SK-MEL-28 cell lysate.

Target description

~55 kDa observed

Physical form

Format: Purified
Protein G Purified
Purified mouse monoclonal IgG1κ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
SK-MEL-28 cell lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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