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Key Documents

MAB3321

Sigma-Aldrich

Anti-MMP-13 Antibody, clone 181-15A12

clone 181-15A12, Chemicon®, from mouse

Synonym(s):

Collagenase-3

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

181-15A12, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable

isotype

IgG1κ

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... MMP13(4322)

Specificity

Reacts with precursor and active forms of human MMP-13 and does not cross-react with human MMP-1, 2, 3, 7, 8, 9. This is a purified mouse moncolonal antibody to recombinant human matrix metalloproteinase 13 (human MMP-13, procollagenase-3).

Application

Anti-MMP-13 Antibody, clone 181-15A12 detects level of MMP-13 & has been published & validated for use in ELISA, WB, IH(P).
Immunoblotting

Immunohistochemistry on paraffin-embedded tissue sections.
Research Category
Cell Structure
Research Sub Category
MMPs & TIMPs

Physical form

Format: Purified
Purified immunoglobulin to recombinant human matrix metalloproteinase 13 (human MMP-13, procollagenase-3). Liquid in 0.1 M PBS, pH 7.0 containing 4% protease free bovine serum albumin.

Storage and Stability

Maintain at -20°C for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Manufactured by Daiichi Fine Chemical Co., Ltd

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Elevated expression of matrix metalloproteinase-13 in abdominal aortic aneurysms.
Gerard Tromp, Zoran Gatalica, Magdalena Skunca, Ramon Berguer, Thomas Siegel et al.
Annals of Vascular Surgery null
J M Del Casar et al.
Breast cancer research and treatment, 116(1), 39-52 (2009-02-26)
An immunohistochemical study was performed using tissue arrays and specific antibodies against MMPs -1, -2, -7, -9, -11, -13, -14, and TIMPs -1, -2 and -3. More than 5,000 determinations on cancer specimens from 124 patients with invasive breast cancer
Lin Xu et al.
Arthritis and rheumatism, 62(9), 2736-2744 (2010-06-03)
To investigate whether the reduction of discoidin domain receptor 2 (DDR-2), a cell membrane tyrosine kinase receptor for native type II collagen, attenuates the progression of articular cartilage degeneration in mouse models of osteoarthritis (OA). Double-heterozygous (type XI collagen-deficient [Col11a1(+/-)]
Tumor necrosis factor receptor superfamily 14 is involved in atherogenesis by inducing proinflammatory cytokines and matrix metalloproteinases.
W H Lee, S H Kim, Y Lee, B B Lee, B Kwon, H Song, B S Kwon, J E Park, W H Lee, S H Kim et al.
Arteriosclerosis, Thrombosis, and Vascular Biology null
Incorporation of vancomycin-supplemented bone incorporation of vancomycin-supplemented bone allografts: radiographical, histopathological and immunohistochemical study in pigs.
Martin A Buttaro, Alejandro M Gonzalez Della Valle, Laura Pi?eiro, Esteban Mocetti et al.
Acta Orthopaedica Scandinavica null

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