GF101
CD40 Ligand/TRAP Protein, Recombinant human
The CD40 Ligand (CD40L/TRAP protein) is a type II membrane protein which, effectuates the helper function of T cells on resting B cells.
Synonym(s):
CD154, TRAP, TNF-related activation protein, T cell antigen Gp39
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About This Item
UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.75
Recommended Products
biological source
human
Quality Level
Assay
>98% (SDS-PAGE and HPLC)
manufacturer/tradename
Chemicon®
technique(s)
cell culture | mammalian: suitable
impurities
<0.1 ng/μg Endotoxin (of sCD40L/TRAP; 1EU/μg)
NCBI accession no.
UniProt accession no.
shipped in
dry ice
Gene Information
human ... CD40LG(959)
General description
CD40 Ligand (CD40L/TRAP) is a type II membrane protein which, effectuates the helper function of T cells on resting B cells. GF101 is a 16.3 kDa protein containing 149 amino acid residues comprising the receptor binding TNF-like domain of CD40L.
Product Source: Recombinant human
Physical form
Sterile filtered and lyophilized from 10 mM Sodium Phosphate, pH 7.5.
Storage and Stability
The lyophilized protein is stable for a few weeks for at room temperature but is best stored at -20ºC. Reconstitute in water to 0.1-1.0 mg/ml. This solution can be diluted into other aqueous buffers and stored at 2-8ºC for one week or -20ºC for future use. Reconstituted sCD40L/TRAP should be stored at -20ºC in undiluted aliquots for up to 6 months. Freeze/thaw cycles will result in significant loss of activity.
Analysis Note
Specific Activity: GF101 is fully biologically active as determined by its ability to stimulate the proliferation of HEK-BlueTMCD40 reporter cells.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Certificates of Analysis (COA)
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