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Key Documents

AB15554

Sigma-Aldrich

Anti-AT2 Receptor Antibody

Chemicon®, from rabbit

Synonym(s):

Angiotensin II receptory type 2, AGTR2

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, rat

should not react with

human

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

NCBI accession no.

NM_000686.4

UniProt accession no.

P50052

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... AGTR2(186)

Specificity

Recognizes AT2 Receptor (Angiotensin II receptory type 2, AGTR2).

Immunogen

Purified peptide from the N-terminus of rat AT2 Receptor (Accession number P35351).

Application

This Anti-AT2 Receptor Antibody is validated for use in WB for the detection of AT2 Receptor.
Western blot: 1:200-1:500 using ECL on rat brain and mouse MS1 cell lysate.
Dilutions should be made using a carrier protein such as BSA (1-3%).

Optimal working dilutions must be determined by the end user.

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.025% sodium azide as a preservative. Reconstitute with 50 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min).

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Hazard Statements

H412

Precautionary Statements

P273 - P501

Hazard Classifications

Aquatic Chronic 3

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Marina C Muñoz et al.
The Journal of endocrinology, 221(2), 215-227 (2014-04-24)
The renin-angiotensin system (RAS) plays a crucial role in the regulation of physiological homeostasis and diseases such as hypertension, coronary artery disease, and chronic renal failure. In this cascade, the angiotensin-converting enzyme (ACE)/angiotensin II (Ang II)/AT1 receptor axis induces pathological
Francine Duchatsch et al.
Journal of the American Society of Hypertension : JASH, 12(8), 605-613 (2018-06-28)
Hypertension is one of the chronic side effects of dexamethasone (DEX) treatment; however, almost nothing is known about its acute effects. Therefore, the aim of this study was to investigate the possible mechanisms involved in blood pressure control after acute
Lucinda M Hilliard Krause et al.
Clinical science (London, England : 1979), 134(7), 871-884 (2020-03-24)
Recently, we designed a group of peptides by sequential substitution of the naturally occurring α-amino acid throughout the Ang III peptide sequence with the corresponding β-amino acid. β-Amino acid substitution at the proline residue of Ang III (β-Pro7-Ang III) resulted

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