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8.56017

Sigma-Aldrich

Fmoc-Thr(tBu)-Wang resin (100-200 mesh)

Novabiochem®

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About This Item

UNSPSC Code:
12352209
NACRES:
NA.22

Quality Level

product line

Novabiochem®

form

beads

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-30°C

General description

Pre-loaded resin for synthesis of peptide acids containing a C-terminal threonine amino-acid residue by Fmoc SPPS.
This pre-loaded Wang resin is prepared using a synthesis-tested base resin, to ensure reproducibility and efficacy in SPPS. Loading of the Fmoc-amino acid is carried out under conditions to minimize enantiomerization and dipeptide formation, the values of which are provided on the COA. The lot number of the batch of Fmoc-amino acid used to prepare the resin is also provided on the COA, to provide transparency and traceability.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Linkage

Replaces: 04-12-2063

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.40 - 1.00 mmol/g
Enantiomeric purity: ≥ 99.5 % (a/a)
Swelling Volume (in DMF): lot specific result
Identity (of the substitution): passes test
Content Dipeptide (HPLC): ≤ 0.5 % (a/a)
Novabiochem Fmoc amino acid: lot number
The qualitiy of this resin has been confirmed by the successful synthesis of the 21mer peptide related to myelin oligodendrocyte glycoprotein (35-55), with an Fmoc-Val-Wang resin made from the same batch of base resin.
The polymer matrix is copoly (styrene - 1% DVB), 100 - 200 mesh.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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