428015

Sodium dodecyl sulfate

>97% (titration)

• Synonym(s): Sodium n-Dodecyl Sulfate, Sodium Lauryl Sulfate, SDS
• Empirical Formula (Hill Notation): C₁₂H₂₅O₄S · Na
• CAS Number: 151-21-3
• Molecular Weight: 288.38
• MDL number: MFCD00036175
• UNSPSC Code: 12161902
• NACRES: NA.21

Properties

• product name: Sodium dodecyl sulfate, An ionic detergent useful in electrophoretic separation of proteins and lipids.
• Quality Level: 100
• Assay: >97% (titration)
• form: solid
• mol wt: micellar wt 18,000
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• aggregation number: 62
• color: white
• CMC: 7-10 mM
• solubility: water: 100 mg/mL
• shipped in: ambient
• storage temp.: 15-25°C
• InChI: 1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
• InChI key: DBMJMQXJHONAFJ-UHFFFAOYSA-M

Description

General description

An ionic detergent useful in electrophoretic separation of proteins and lipids (aggregation number: 62; CMC: 7-10 mM; micellar weight: 18,000).

Application

• Construction of dental pulp decellularized matrix by cyclic lavation combined with mechanical stirring and its proteomic analysis.: This study details the use of sodium dodecyl sulfate (SDS) in creating a dental pulp decellularized matrix through cyclic lavation and mechanical stirring, followed by proteomic analysis to identify the resulting protein composition. (Zhang et al., 2024).


• Polycarbonate Ultracentrifuge Tube Re-use in Proteomic Analyses of Extracellular Vesicles.: The research explores the reusability of polycarbonate ultracentrifuge tubes in proteomic analyses of extracellular vesicles, utilizing SDS for efficient protein extraction and quantification. (Cahalane et al., 2024).


• Identification of protein components of the transformation system in the cell line of immortalized human keratinocytes HaCaT exposed to surfactants.: This study identifies protein components in HaCaT cells exposed to surfactants, including SDS, providing insights into cellular transformations induced by these chemicals. (Shkrigunov et al., 2024).


• Assessing the precision of a detergent-assisted cartridge precipitation workflow for non-targeted quantitative proteomics.: The research assesses the precision of a detergent-assisted precipitation workflow using SDS for non-targeted quantitative proteomics, demonstrating its utility in protein sample preparation. (Nickerson et al., 2024).

Warning

Toxicity: Harmful (C)

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H315,H318,H412
• Precautionary Statements: P264 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): 338.0 °F
• Flash Point(C): 170 °C