Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

More Documents

407317

Sigma-Aldrich

Anti-Integrin β₆ Mouse mAb (442.5C4)

liquid, clone 442.5C4, Calbiochem®

Synonym(s):

Integrin β₆ Detection Antibody, Mouse Anti-Integrin β₆

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12352203
NACRES:
NA.43

biological source

mouse

Quality Level

100

antibody form

ascites fluid

antibody product type

primary antibodies

clone

442.5C4, monoclonal

form

liquid

does not contain

preservative

species reactivity

human

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

isotype

IgG

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ITGB6(3694)

Related Categories

General description

Mouse monoclonal antibody supplied as undiluted ascites. Recognizes the β6 integrin chain.
Recognizes the β6 integrin chain.
This Anti-Integrin β₆ Mouse mAb (442.5C4) is validated for use in ELISA, FC, Immunoblotting, IP, Paraffin Sections for the detection of Integrin β₆.

Immunogen

Human
recombinant, human αvβ₆

Application

ELISA (see comments)

Flow Cytometry (1:50-1:100)

Immunoblotting (1:50-1:100)

Immunoprecipitation (1:50-1:100)

Paraffin Sections (1:50-1:100)

Warning

Toxicity: Standard Handling (A)

Physical form

Undiluted ascites.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Miller, L.A., et al. 2001. J. Histochem. Cytochem.49, 41.
Breuss, J.M., et al. 1995. J. Cell Sci.108, 2241.
Hynes, R.O. 1992. Cell.69, 11.
Albelda, S.M. and Buck, C.A. 1990. FASEB J.4, 2868.
Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol.3, 179.
Hynes, R.O. 1987. Cell.45, 549.
This antibody has also been reported to work for ELISA. Variables associated with assay conditions will dictate the proper working dilution.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Ludmila Prudkin et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 22(5), 668-678 (2009-03-10)
Epithelial-to-mesenchymal transition is a process in which cells undergo a developmental switch from an epithelial to a mesenchymal phenotype. We investigated the role of this phenomenon in the pathogenesis and progression of adenocarcinoma and squamous cell carcinoma of the lung.
Johannes Notni et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 58(4), 671-677 (2016-12-17)
Expression of the cellular transmembrane receptor αvβ6 integrin is essentially restricted to malignant epithelial cells in carcinomas of a broad variety of lineages, whereas it is virtually absent in normal adult tissues. Thus, it is a highly attractive target for

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service