14-724

CLK3 Protein, active, 10 µg

• UNSPSC Code: 12352202
• eCl@ss: 32160405

Properties

• recombinant: expressed in baculovirus infected Sf21 cells
• Quality Level: 100
• description: protein target CLK3
• purified by: (Ni²⁺/NTA-agarose)
• technique(s): activity assay: suitable
• UniProt accession no.: P49761
• Gene Information: human ... CLK3(1198)

Description

General description

FUNCTION: SwissProt: P49761 # Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates serines, threonines and tyrosines.
SIZE: 638 amino acids; 73515 Da
SUBCELLULAR LOCATION: Nucleus. Cytoplasm (By similarity). Acrosome (By similarity).
PTM: Autophosphorylates on all three types of residues (By similarity).
SIMILARITY: SwissProt: P49761 ## Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily. & Contains 1 protein kinase domain.

Quality

routinely evaluated by phosphorylation of 500μM PKC Substrate Peptide 2 (Catalog # 12-411)

Physical properties

63kDa

Storage and Stability

6 months at -70°C from date of shipment

Analysis Note

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2