890895C

18:1 TAP (DOTAP, MS Salt)

Avanti Polar Lipids 890895C

• Synonym(s): 1,2-dioleoyl-3-trimethylammonium-propane (methyl sulfate salt)
• Empirical Formula (Hill Notation): C₄₃H₈₃NO₈S
• CAS Number: 144189-73-1
• Molecular Weight: 774.19
• UNSPSC Code: 12352211

Properties

• form: liquid
• packaging: pkg of 1 × 2.5 mL (890895C-25mg); pkg of 2 × 4 mL (890895C-200mg)
• manufacturer/tradename: Avanti Polar Lipids 890895C
• concentration: 10 mg/mL (890895C-25mg); 25 mg/mL (890895C-200mg)
• lipid type: cationic lipids; transfection
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H]C(C[N+](C)(C)C)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.O=S([O-])(OC)=O
• InChI: 1S/C42H80NO4.CH4O4S/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;1-5-6(2,3)4/h20-23,40H,6-19,24-39H2,1-5H3;1H3,(H,2,3,4)/q+1;/p-1/b22-20-,23-21-;
• InChI key: RSMRWWHFJMENJH-LQDDAWAPSA-M

Description

Biochem/physiol Actions

DOTAP (1,2-dioleoyl-3-trimethylammonium-propane) is a cationic lipid, used for in vitro and in vivo nucleic acid and protein delivery. The lipid composition and cell type affects the transfection potential of DOTAP. DOTAP mediates gene knockdown technique in hematopoietic stem cells (HSCs).

Packaging

5 mL Clear Glass Sealed Ampule (890895C-200mg)

5 mL Clear Glass Sealed Ampule (890895C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372
• Precautionary Statements: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flash Point(F): does not flash
• Flash Point(C): does not flash