880346P

DChemsPC

Avanti Polar Lipids 880346P, powder

• Synonym(s): 1,2-dicholesterylhemisuccinoyl-sn-glycero-3-phosphocholine
• Empirical Formula (Hill Notation): C₇₀H₁₁₆NO₁₂P
• CAS Number: 1155878-69-5
• Molecular Weight: 1194.64
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• form: powder
• packaging: pkg of 1 × 25 mg (880346P-25mg)
• manufacturer/tradename: Avanti Polar Lipids 880346P
• lipid type: cardiolipins; phospholipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: O=P([O-])(OCC[N+](C)(C)C)OC[C@H](OC(CCC(OC1CC[C@]2(C)C(C1)=CCC3C2CC[C@]4(C)C3CC[C@H]4[C@@H](C)CCCC(C)C)=O)=O)COC(CCC(OC5CC[C@]6(C)C(C5)=CCC7C6CC[C@]8(C)C7CC[C@H]8[C@@H](C)CCCC(C)C)=O)=O

Description

Application

DChemsPC might be used:

• as a substitute for cholesterol in liposome formulation to study its effect on membrane stability
• in the preparation of pH-gradient liposomes
• to form sterol-phospholipid hybrid with palmitoyl-2-cholesterylhemisuccinoyl-sn-glycero-3-phosphocholine (PCholPC) and to study its properties and interactions

Biochem/physiol Actions

Liposome instability in blood is caused mainly due to cholesterol exchange. Sterol modified phospholipid retains the bilayer-stabilizing effect of free cholesterol, inhibiting its transfer from the bilayer. Therefore, disterolphospholipids are ideal for liposome preparation. The use of DChemsPC in liposomes prevents content leaking into the serum.

Packaging

5 mL Amber Glass Screw Cap Vial (880346P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3