878120P

C18 Lyso PAF

Avanti Polar Lipids 878120P, powder

• Synonym(s): 1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphocholine
• Empirical Formula (Hill Notation): C₂₆H₅₆NO₆P
• CAS Number: 74430-89-0
• Molecular Weight: 509.70
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• form: powder
• packaging: pkg of 1 × 5 mg (878120P-5mg)
• manufacturer/tradename: Avanti Polar Lipids 878120P
• lipid type: bioactive lipids; phosphoglycerides
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COCCCCCCCCCCCCCCCCCC
• InChI: 1S/C26H56NO6P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-22-31-24-26(28)25-33-34(29,30)32-23-21-27(2,3)4/h26,28H,5-25H2,1-4H3/t26-/m1/s1
• InChI key: XKBJVQHMEXMFDZ-AREMUKBSSA-N

Description

General description

C18-lysoPAF, also known as 1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphocholine, is a synthetic lyso-platelet activating factor (PAF). It is a precursor and metabolite of 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine (C18:0 PAF). Lyso-platelet activating factor (PAF) is synthesized from PAF acetylhydrolases by the degradation of PAF. Additionally, it is also synthesized in the remodeling pathway from 1-O-alkyl-2-arachidonoyl-sn-glycero-3-phosphocholine (1-alkyl-phosphatidylcholine) by the enzyme phospholipase.

Application

C18-lysoPAF (1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphocholine) has been used to study its effect on human eosinophil degranulation.

Packaging

5 mL Amber Glass Screw Cap Vial (878120P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable