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850475C

Avanti

18:1-16:0 PC

1-oleoyl-2-palmitoyl-sn-glycero-3-phosphocholine, chloroform

Synonym(s):

1--(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine; OPPC; PC(18:1(9Z)/16:0)

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About This Item

Empirical Formula (Hill Notation):
C42H82NO8P
CAS Number:
59491-62-2
Molecular Weight:
760.08
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850475C-25mg)
pkg of 2 × 4 mL (850475C-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850475C

concentration

10 mg/mL (850475C-25mg)
25 mg/mL (850475C-200mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-24-26-28-30-32-34-41(44)48-38-40(39-50-52(46,47)49-37-36-43(3,4)5)51-42(45)35-33-31-29-27-25-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1

InChI key

RRVPPYNAZJRZFR-VYOBOKEXSA-N

General description

Phosphatidylcholines (PCs) are mainly located on the outer leaflets of the biological membrane bilayer.

Application

18:1-16:0 PC (1-oleoyl-2-palmitoyl-sn-glycero-3-phosphocholine) may be used:
  • as a lipid standard in ultra-performance liquid chromatography (UPLC) analyses
  • as a component in liposomes to study the cell proliferation of several cell lines
  • in liposomes for cross-linking experiment

Biochem/physiol Actions

Phosphatidylcholine (PC) serves as a major source for eicosanoids.

Packaging

5 mL Clear Glass Sealed Ampule (850475C-200mg)
5 mL Clear Glass Sealed Ampule (850475C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Liver,Kidney, Respiratory system

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Analytical and bioanalytical chemistry, 411(4), 915-924 (2018-12-24)
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Eun A Ra et al.
Nature communications, 7, 11726-11726 (2016-05-25)
Autophagy is responsible for the bulk degradation of cytosolic constituents and plays an essential role in the intestinal epithelium by controlling beneficial host-bacterial relationships. Atg5 and Atg7 are thought to be critical for autophagy. However, Atg5- or Atg7-deficient cells still
Jone Garate et al.
Journal of the American Society for Mass Spectrometry, 31(3), 517-526 (2020-03-05)
Imaging mass spectrometry (IMS) is becoming an essential technique in lipidomics. Still, many questions remain open, precluding it from achieving its full potential. Among them, identification of species directly from the tissue is of paramount importance. However, it is not
Takao Hanada et al.
The Journal of biological chemistry, 282(52), 37298-37302 (2007-11-08)
Autophagy is a bulk degradation process in eukaryotic cells; autophagosomes enclose cytoplasmic components for degradation in the lysosome/vacuole. Autophagosome formation requires two ubiquitin-like conjugation systems, the Atg12 and Atg8 systems, which are tightly associated with expansion of autophagosomal membrane. Previous
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