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840064C

Avanti

18:0-20:4 PS

1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-L-serine (sodium salt), chloroform

Synonym(s):

1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); SAPS; PS(18:0/20:4(5Z,8Z,11Z,14Z)); 110673

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About This Item

Empirical Formula (Hill Notation):
C44H77NO10PNa
CAS Number:
474967-15-2
Molecular Weight:
834.05
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (840064C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 840064C

concentration

10 mg/mL (840064C-25mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C44H78NO10P.Na/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-43(47)55-40(38-53-56(50,51)54-39-41(45)44(48)49)37-52-42(46)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2;/h11,13,17,19,22,24,28,30,40-41H,3-10,12,14-16,18,20-21,23,25-27,29,31-39,45H2,1-2H3,(H,48,49)(H,50,51);/q;+1/p-1/b13-11-,19-17-,24-22-,30-28-;/t40-,41+;/m1./s1

InChI key

PKENGTIYXZLXFZ-PTPAXTOESA-M

General description

18:0-20:4 PS or 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-L-serine is an asymmetric saturated-polyunsaturated phospholipid.

Application

18:0-20:4 PS or 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-L-serine (sodium salt) has been used in the preparation of liposomes to study the effects of the fatty acid (FA) profile of phospholipids on membrane vesiculation by dynamin and endophilin.

Packaging

5 mL Clear Glass Sealed Ampule (840064C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Certificates of Analysis (COA)

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Marco M Manni et al.
eLife, 7 (2018-03-16)
Phospholipid membranes form cellular barriers but need to be flexible enough to divide by fission. Phospholipids generally contain a saturated fatty acid (FA) at position sn1 whereas the sn2-FA is saturated, monounsaturated or polyunsaturated. Our understanding of the impact of
Peter A Leventis et al.
Annual review of biophysics, 39, 407-427 (2010-03-03)
Phosphatidylserine (PS) is the most abundant negatively charged phospholipid in eukaryotic membranes. PS directs the binding of proteins that bear C2 or gamma-carboxyglutamic domains and contributes to the electrostatic association of polycationic ligands with cellular membranes. Rather than being evenly

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