QBD10278

m-dPEG^®₈-amine

• Synonym(s): 2-[2-[2-[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine, 3,6,9,12,15,18,21,24-Octaoxapentacosan-1-amine, Polyethylene glycol
• Empirical Formula (Hill Notation): C₁₇H₃₇NO₈
• CAS Number: 869718-81-0
• Molecular Weight: 383.48
• MDL number: MFCD13184961
• UNSPSC Code: 12352116
• PubChem Substance ID: 329823905
• NACRES: NA.22

Properties

• Assay: >90%
• form: solid or viscous liquid
• reaction suitability: reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: carboxyl reactive
• polymer architecture: shape: linear; functionality: monofunctional
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: COCCOCCOCCOCCOCCOCCOCCOCCN
• InChI: 1S/C17H37NO8/c1-19-4-5-21-8-9-23-12-13-25-16-17-26-15-14-24-11-10-22-7-6-20-3-2-18/h2-18H2,1H3
• InChI key: YXWBFPPGROXJLL-UHFFFAOYSA-N

Description

Features and Benefits

The m-dPEG^®₈-amine provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG^® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG^® reagent can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG^®₈-amine reacts with carboxylic acids and active esters.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable