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Key Documents

ALD00444

Sigma-Aldrich

Late Stage Functionalization Toolkit

Synonym(s):

Baran Late-Stage Functionalization Kit, LSF Toolkit featuring Baran Diversinates

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About This Item

UNSPSC Code:
41116155
NACRES:
NA.22

storage temp.

2-8°C

Application

The Baran Late-Stage Toolkit is a convenient collection of 12 highly innovative reagents that are highly effective in the diversification of complex molecules. The contents in the box are 11 Baran Diversinates and one vial of Palau′Chlor® in amounts of 100 mg each. For obtaining larger amounts of any desired kit component, see the kit component table at the bottom of the page.

Useful Topics:
Late Stage Functionalization

Baran Group – Professor Product Portal

Palau′Chlor
Diversinates

Legal Information

Diversinates is a trademark of Sigma-Aldrich Co. LLC
Palau'Chlor is a registered trademark of Merck KGaA, Darmstadt, Germany

Kit Components Also Available Separately

Product No.
Description
SDS

  • 745480Zinc isopropylsulfinate, 95%SDS

  • 745405Sodium 1,1-difluoroethanesulfinateSDS

  • 745499Zinc trifluoroethanesulfinateSDS

  • 767840Zinc difluoromethanesulfinate, 95%SDS

  • 771406Zinc trifluoromethanesulfinateSDS

  • ALD00288Sodium tert-butylsulfinateSDS

  • ALD00290Sodium 2,2-dimethylpropylsulfinateSDS

  • 792454Palau′Chlor®, 95%SDS

  • 790184Sodium 1-(trifluoromethyl)cyclopropanesulfinateSDS

  • 790796Zinc benzylsulfinateSDS

  • ALD00230Sodium 4,4-difluorocyclohexanesulfinateSDS

  • ALD00232Sodium tetrahydropyransulfinateSDS

See All (12)

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

8A - Combustible corrosive hazardous materials


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A C?H Methylation Reaction of Heteroarenes Inspired by Radical SAM Methyl Transferase.
Gui J, et al.
Journal of the American Chemical Society, 136, 4853-4856 (2014)
Simple Sulfinate Synthesis Enables C-H Trifluoromethylcyclopropanation
Gianatassio R, et al.
Angewandte Chemie (International Edition in English), 53, 9851-9855 (2014)
Radical C?H Functionalization of Heteroarenes under Electrochemical Control.
O'Brien, et al.
Angewandte Chemie (International Edition in English), 53, 11868-11871 (2014)
Palau'chlor: A Practical and Reactive Chlorinating Reagent
Rodriguez RA, et al.
Journal of the American Chemical Society, 136, 6908-6911 (2014)
Yuta Fujiwara et al.
Journal of the American Chemical Society, 134(3), 1494-1497 (2012-01-11)
Molecular scaffolds containing alkylfluorine substituents are desired in many areas of chemical research from materials to pharmaceuticals. Herein, we report the invention of a new reagent (Zn(SO(2)CF(2)H)(2), DFMS) for the innate difluoromethylation of organic substrates via a radical process. This

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