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A59522

Sigma-Aldrich

2-Aminoindan hydrochloride

98%

Synonym(s):

2-Indanamine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C9H11N · HCl
CAS Number:
2338-18-3
Molecular Weight:
169.65
Beilstein:
3913700
EC Number:
219-048-0
MDL number:
MFCD00012549
UNSPSC Code:
12352100
PubChem Substance ID:
24891039
NACRES:
NA.22

Quality Level

100

Assay

98%

form

crystals

mp

245-247 °C (lit.)

SMILES string

Cl[H].NC1Cc2ccccc2C1

InChI

1S/C9H11N.ClH/c10-9-5-7-3-1-2-4-8(7)6-9;/h1-4,9H,5-6,10H2;1H

InChI key

XEHNLVMHWYPNEQ-UHFFFAOYSA-N

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Application

Prepared from 2-indanols via azide displacement and subsequent hydrogenation.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Tetrahedron, 61, 6801-6801 (2005)
Loanda R Cumba et al.
The Analyst, 140(16), 5536-5545 (2015-06-24)
"Synthacaine" is a New Psychoactive Substance which is, due to its inherent psychoactive properties, reported to imitate the effects of cocaine and is therefore consequently branded as "legal cocaine". The only analytical approach reported to date for the sensing of
S X Ma et al.
The Journal of pharmacology and experimental therapeutics, 256(2), 751-756 (1991-02-01)
Dopaminergic structure-activity relationships of 2-aminoindans were evaluated for their ability to inhibit responses to stimulation of cardioaccelerator nerves in cats. The major observations were as follows: 1) Unsubstituted di-n-propyl- and diethyl 2-aminoindan derivatives do not inhibit responses to stimulation of
J G Cannon et al.
Journal of medicinal chemistry, 29(10), 2016-2020 (1986-10-01)
The ortho hydroxy/methyl, hydroxy/hydroxymethyl, hydroxy/formyl, and hydroxy/carboxy substitution patterns, some of which confer dopaminergic agonist effects upon 2-aminotetralin ring systems, have been incorporated into beta-phenethylamine, 2-aminoindan, and trans-octahydrobenzo[f]quinoline rings. Certain of the 2-aminoindan derivatives displayed pharmacologic properties consistent with their
W Dimpfel et al.
BMC pharmacology, 11, 2-2 (2011-02-23)
Rasagiline, a new drug developed to treat Parkinson's disease, is known to inhibit monoamine oxidase B. However, its metabolite R-(-)-aminoindan does not show this kind of activity. The present series of in vitro experiments using the rat hippocampal slice preparation
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