913286
Methoxypolyethylene epoxide
PEG average Mn 750
Synonym(s):
Epoxide PEG, mPEG-epoxide
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About This Item
Linear Formula:
C3H5O2(C2H4O)nCH3
UNSPSC Code:
43211915
NACRES:
NA.23
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form
semisolid
mol wt
PEG average Mn 750
average Mn 750 (by NMR)
color
white to off-white
Ω-end
(epoxide)
α-end
methoxy
polymer architecture
shape: linear
functionality: monofunctional
storage temp.
2-8°C
Related Categories
Application
Epoxide functionalized PEG can be covalently bonded to polymers and biopolymers by epoxide ring-opening reactions. As a surface coating, PEGylated surfaces prevent cell adhesion by entropically driven steric repulsion. For drug delivery, PEGylation increases the hydrophilicity of the drug carrier.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Rajesh Kumar Kainthan et al.
Biomacromolecules, 9(3), 886-895 (2008-02-06)
This paper discusses the binding and release properties of hydrophobically modified hyperbranched polyglycerol-polyethylene glycol copolymers that were originally developed as human serum albumin (HSA) substitutes. Their unimolecular micellar nature in aqueous solution has been proven by size measurements and other
Mohamed H Ramadan et al.
Langmuir : the ACS journal of surfaces and colloids, 30(25), 7485-7495 (2014-06-04)
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Simone M Haag et al.
Nature, 559(7713), 269-273 (2018-07-06)
Aberrant activation of innate immune pathways is associated with a variety of diseases. Progress in understanding the molecular mechanisms of innate immune pathways has led to the promise of targeted therapeutic approaches, but the development of drugs that act specifically
Jameel Ahmad Khan et al.
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