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902268

Sigma-Aldrich

seMpai

Synonym(s):

DP3-Na, TokeOni analogue, water-soluble NIR emission luciferin analogue, 2-[(1E,3E)-6-[3-(dimethylamino)pyridine]-1,3-butadien-1-yl]-4,5-dihydro-(4S)-4-thiazolecarboxylic acid sodium salt

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About This Item

Empirical Formula (Hill Notation):
C15H16N3NaO2S
Molecular Weight:
325.36
UNSPSC Code:
12352106
NACRES:
NA.23

description

Purity: mixture of D (80% min.) and L (20% max.) forms

form

powder

color

black to yellow-brown

storage temp.

−20°C

General description

2-[(1E,3E)-6-[3-(dimethylamino)pyridine]-1,3-butadien-1-yl]-4,5-dihydro-(4S)-4-thiazolecarboxylic acid sodium salt (DP3-Na) is a new NIR emission luciferin analog having luminescence peak at 670 ~ 680 nm with a peak range in the near-infrared (NIR) region with the enhanced solubility in water.
Luciferin is a generic term for the light-emitting compound found in organisms that generate bioluminescence.

Application

Applications:
  • Bioimaging
  • In vivo imaging

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Quantum yield improvement of red-light-emitting firefly luciferin analogues for in vivo bioluminescence imaging
Kiyama M, et al.
Tetrahedron, 74(6), 652- 660 (2018)

Articles

Overall results suggest that seMpai is a suitable substrate of near-infrared BLI for many biological experiments. Its high solubility in neutral buffer conditions further extends the bioluminescent application of TokeOni derivatives.

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