901311
Polyester bis-MPA dendron 2 NHBoc, 1 azide (core)
generation 1
Synonym(s):
Bis-MPA dendron, PFd-G1-Azide-NH-BOC
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C27H47N5O10
Molecular Weight:
601.69
UNSPSC Code:
12352125
NACRES:
NA.23
description
2 NHBoc, 1 azide (core)
Quality Level
form
solid
mol wt
generation 1
no. Surface Groups
2
color
white to off-white
functional group
azide (core)
storage temp.
−20°C
General description
- Polymer architecture: Dendron
- End Group Functionality: Boc-protected amine
- Boc: tert-Butyloxycarbonyl
- Bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid
Application
Bis-MPA (or 2,2-Bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers. Dendrons synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research applications. These materials have been used in many applications such as signal amplification in bioassays and in drug delivery applications. After Boc deprotection, amine-functionalized dendrons can be readily used in EDC or DCC coupling reactions with carbonyl-containing compounds to yield highly functionalized materials for a variety of biomedical applications. Addionally, the azide-core can be readily conjugated using either copper(I)-catalyzed alkyne-azide cycloaddition (CuAAC) or strain-promoted alkyne-azide cycloaddition (SPAAC).
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Anna Carlmark et al.
Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service