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760897

Sigma-Aldrich

Poly(ethylene glycol), 32 hydroxyl dendron, generation 4

average Mn 24,000

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About This Item

UNSPSC Code:
12162002
NACRES:
NA.23

description

hydroxyl surface groups

Quality Level

100

form

powder

mol wt

PEG Mn 20,000 (n~450; esterified with 16 OH groups)
PEG average Mn 20,000
average Mn 24,000

feature

generation 4

no. Surface Groups

32

transition temp

Tm 56-61 °C

functional group

hydroxyl

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General description

Dendrimers are symmetrically branched polymer structures and monodispersed macromolecules. They possess uniform size, water solubiltity, and modifiable surface functionality. Cross linking with polyethylene glycol results in very high water content.

Application

1. Dendritic nanodevices for therapeutic applications.
2. Surface modified for targeting, imaging and drug delivery
3. Antibody-dendrimer conjugate
4. Anti viral drugs
5. Tissue repair scaffolds

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Anil K Patri et al.
Current opinion in chemical biology, 6(4), 466-471 (2002-07-23)
Dendrimers are synthetic, highly branched, mono-disperse macromolecules of nanometer dimensions. Started in the mid-1980s, the research investigations into the synthetic methodology, physical and chemical properties of these macromolecules are increasing exponentially with growing interest in this field. Potential applications for
Degradable Poly(ethylene glycol) Hydrogels
for 2D and 3D Cell Culture
Kasko A
Material Matters, 6(3), 67-75 null

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