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Key Documents

705004

Sigma-Aldrich

Poly(ethylene glycol) dithiol

average Mn 8,000

Synonym(s):

PEG dithiol ca. 8,000, Poly(ethylene glycol)-dithiol, average Mn 8,000, PEG dithiol

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About This Item

Linear Formula:
HSCH2CH2(OCH2CH2)nSH
UNSPSC Code:
12162002
NACRES:
NA.23

form

powder

mol wt

average Mn 8,000

reaction suitability

reagent type: cross-linking reagent
reactivity: thiol reactive

mp

63-67 °C

Ω-end

thiol

α-end

thiol

polymer architecture

shape: linear
functionality: homobifunctional

storage temp.

2-8°C

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Storage Class Code

13 - Non Combustible Solids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Articles

The use of hydrogel-based biomaterials for the delivery and recruitment of cells to promote tissue regeneration in the body is of growing interest. This article discussed the application of hydrogels in cell delivery and tissue regeneration.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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