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Sigma-Aldrich

Fmoc-His(Trt)-OH

≥98.0% (sum of enantiomers, HPLC), for peptide synthesis

Synonym(s):

Nα-Fmoc-N(im)-trityl-L-histidine

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About This Item

Empirical Formula (Hill Notation):
C40H33N3O4
CAS Number:
109425-51-6
Molecular Weight:
619.71
Beilstein:
5204720
MDL number:
MFCD00043332
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
57651056
NACRES:
NA.26

product name

Fmoc-His(Trt)-OH, ≥98.0% (sum of enantiomers, HPLC)

Assay

≥98.0% (sum of enantiomers, HPLC)

optical activity

[α]/D 87±5°, c = 1 in chloroform

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

SMILES string

OC(=O)[C@H](Cc1cn(cn1)C(c2ccccc2)(c3ccccc3)c4ccccc4)NC(=O)OCC5c6ccccc6-c7ccccc57

InChI

1S/C40H33N3O4/c44-38(45)37(42-39(46)47-26-36-34-22-12-10-20-32(34)33-21-11-13-23-35(33)36)24-31-25-43(27-41-31)40(28-14-4-1-5-15-28,29-16-6-2-7-17-29)30-18-8-3-9-19-30/h1-23,25,27,36-37H,24,26H2,(H,42,46)(H,44,45)/t37-/m0/s1

InChI key

XXMYDXUIZKNHDT-QNGWXLTQSA-N

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Application

Fmoc-His(Trt)-OH can be used as a building block in solid-phase peptide synthesis (SPPS).

Analysis Note

may contain ~1 equivalent solvent

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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