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450561

Sigma-Aldrich

11-Mercaptoundecanoic acid

95%

Synonym(s):

MUA, MUDA

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About This Item

Linear Formula:
HS(CH2)10CO2H
CAS Number:
Molecular Weight:
218.36
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.23

Assay

95%

form

solid

mp

46-50 °C (lit.)

SMILES string

OC(=O)CCCCCCCCCCS

InChI

1S/C11H22O2S/c12-11(13)9-7-5-3-1-2-4-6-8-10-14/h14H,1-10H2,(H,12,13)

InChI key

GWOLZNVIRIHJHB-UHFFFAOYSA-N

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General description

11-Mercaptoundecanoic acid (MUA) is used as a self-assembled monolayer (SAM) which has a long alkane chain and carboxyl containing thiols. MUA is highly packed and has self-organized surface monolayers. It is a pH responsive ligand which facilitates the dispersion of nanoparticles into water and solvent based media.

Application

MUA as a self-assembled monolayer (SAM) is used as a microfluidic integrated surface plasmon resonance (SPR) for detection and quantification of bacteria in medical diagnostics. It is also used to bio-functionalize the screen printed gold electrodes (SPGEs) that are used for the detection and quantification of dengue. It also forms monolayers on gold nanoparticles (AuNPs) attached via thiol groups. MUA incorporated AuNPs exhibit excellent fluorescence properties which may be used for metal ion detection in serum samples.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

No data available

Flash Point(C)

No data available

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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11-Mercaptoundecanoic acid functionalized gold nanoclusters as fluorescent probes for the sensitive detection of Cu2+ and Fe3+ ions.
Bai Z, et al.
Chinese Chemical Letters = Zhongguo Hua Xue Kuai Bao, 28(9), 1901-1904 (2017)
Electrochemical lateral flow immunosensor for detection and quantification of dengue NS1 protein.
Sinawang PD, et al.
Biosensors And Bioelectronics, 77(5), 400-408 (2016)
Alexey Ivanov et al.
Talanta, 194, 723-730 (2019-01-06)
Reversible inhibitors of acetylcholinesterase are increasingly applied in the Alzheimer's disease therapy. Their determination with biosensors requires special attention to the enzyme immobilization due to importance of electrostatic and steric factors affecting accessibility of the active site to the substrate
Li Han et al.
Langmuir : the ACS journal of surfaces and colloids, 20(14), 6019-6025 (2006-02-08)
The preparation of nanocomposite materials from carbon nanotubes (CNTs) and metal or metal oxide nanoparticles has important implications to the development of advanced catalytic and sensory materials. This paper reports findings of an investigation of the preparation of nanoparticle-coated carbon
Portable microfluidic integrated plasmonic platform for pathogen detection.
Tokel O, et al.
Scientific Reports, 5(5), 9152-9152 (2015)

Articles

Inorganic nanomaterials are tunable by size, shape, structure, and/or composition. Advances in the synthesis of well-defined nanomaterials have enabled control over their unique optical, electronic, and chemical properties stimulating tremendous interest across a wide range of disciplines. This article illuminates some of the recent research advances of inorganic nanoparticles (NPs) in optoelectronics applications.

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