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448877

Sigma-Aldrich

Chitosan

medium molecular weight

Synonym(s):

Deacetylated chitin, Poly(D-glucosamine)

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.23

form

powder

viscosity

200-800 cP, 1 wt. % in 1% acetic acid(25 °C, Brookfield)(lit.)

solubility

dilute aqueous acid: soluble

InChI

1S/C56H103N9O39/c1-87-56(86)65-28-38(84)46(19(10-74)96-55(28)104-45-18(9-73)95-49(27(64)37(45)83)97-39-12(3-67)88-47(85)20(57)31(39)77)103-54-26(63)36(82)44(17(8-72)94-54)102-53-25(62)35(81)43(16(7-71)93-53)101-52-24(61)34(80)42(15(6-70)92-52)100-51-23(60)33(79)41(14(5-69)91-51)99-50-22(59)32(78)40(13(4-68)90-50)98-48-21(58)30(76)29(75)11(2-66)89-48/h11-55,66-85H,2-10,57-64H2,1H3,(H,65,86)/t11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48+,49+,50+,51+,52+,53+,54+,55+/m1/s1

InChI key

FLASNYPZGWUPSU-SICDJOISSA-N

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Application

Chitosan may be used as a flocculant, in protein precipitation, encapsulating agent and aqueous thickener.
Forms gels with multivalent anions. Gives clear solutions that dry to strong, clear films.

Features and Benefits

Biocompatible, antibacterial and environmentally friendly polyelectrolyte with a variety of applications including water treatment, chromatography, additives for cosmetics, textile treatment for antimicrobial activity, novel fibers for textiles, photographic papers, biodegradable films, biomedical devices, and microcapsule implants for controlled release in drug delivery.

Physical form

75-85% deacetylated

Storage Class Code

11 - Combustible Solids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Viviana Vergaro et al.
International journal of biological macromolecules, 99, 187-195 (2017-02-25)
Carbohydrate polimeric microcapsules were assembled using a LbL approach onto a CaCO
Enni Hakkarainen et al.
Pharmaceutics, 11(10) (2019-09-29)
We investigated nozzleless ultrasound-enhanced electrospinning (USES) as means to generate nanofibrous drug delivery systems (DDSs) for pharmaceutical and biomedical applications. Traditional electrospinning (TES) equipped with a conventional spinneret was used as a reference method. High-molecular polyethylene oxide (PEO) and chitosan
Arnout Mieremet et al.
PloS one, 12(3), e0174478-e0174478 (2017-03-24)
Full thickness human skin models (FTMs) contain an epidermal and a dermal equivalent. The latter is composed of a collagen dermal matrix which harbours fibroblasts. Current epidermal barrier properties of FTMs do not fully resemble that of native human skin
Paulo V O Toledo et al.
International journal of biological macromolecules, 123, 1180-1188 (2018-11-24)
Xanthan gum (XG) was applied for the creation of hydrophilic, hydrophobic and layered cryogels. Firstly, the correlation among synthesis parameters, such as solvent composition and polymer concentration (Cp) in the precursor gel and mold diameter (Φ), with physicochemical properties and
Lana Glerieide Silva Garcia et al.
Carbohydrate polymers, 195, 662-669 (2018-05-29)
Difficulties in the treatment of Candida spp. invasive infections are usually related to the formation of biofilms. The aim of this study was to determine the effects of molecular weight (MW) of chitosan (using high (HMW), medium (MMW) and low

Articles

Microparticles with controlled size and morphology are of significant interest in the fields of drug delivery and biopharmaceuticals.

Chitin, a natural polysaccharide, is the second most abundant natural biopolymer in the world, after cellulose.

The development of new medical devices and pharmaceuticals plays an integral role in the medical industry. Both natural and synthetic polymers possess benefits that make them valuable components in therapeutics.

Chitosan Biopolymer from Fungal Fermentation for Delivery of Chemotherapeutic Agents

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