Skip to Content
MilliporeSigma
All Photos(3)

Key Documents

View All Documentation

400173

Sigma-Aldrich

Lithium tert-butoxide

97%

Synonym(s):

LiOtBu

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Linear Formula:
(CH3)3COLi
CAS Number:
1907-33-1
Molecular Weight:
80.05
Beilstein:
3620018
EC Number:
217-611-5
MDL number:
MFCD00050479
UNSPSC Code:
12352300
PubChem Substance ID:
24864902
NACRES:
NA.22

Assay

97%

form

powder and chunks

SMILES string

[Li+].CC(C)(C)[O-]

InChI

1S/C4H9O.Li/c1-4(2,3)5;/h1-3H3;/q-1;+1

InChI key

LZWQNOHZMQIFBX-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Lithium tert-butoxide (LiOtBu) is a weakly basic and nucleophilic alkali metal oxide commonly used as an initiator for anionic polymerization.
Other synthetic applications:
  • In combination with potassium diisopropylamide, LiOtBu can be used to deprotonate 1-(phenylseleno) alkenes and bis (phenylseleno) acetals.
  • LiOtBu can mediate the α-alkylation reaction of ketones with primary alcohols in the absence of any transition metal catalyst.
  • LiOtBu is an effective base for the synthesis of 3,4,5-trisubstituted 3H-oxazol-2-ones and 3,4-disubstituted (Z)-oxazolidin-2-ones from substituted propargyl alcohols and aryl/alkyl isocyanates using DMF as a solvent.

Signal Word

Danger

Hazard Statements

H251,H302,H314

Hazard Classifications

Acute Tox. 4 Oral - Self-heat. 1 - Skin Corr. 1B

Supplementary Hazards

EUH014

Storage Class Code

4.2 - Pyrophoric and self-heating hazardous materials

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SHBD1745V
SHBK4610
SHBK2374
SHBJ9872
SHBH2066V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

The role of association/complexation equilibria in the anionic polymerization of (meth) acrylates.
Kunkel D, et al.
Macromolecular Symposia, 60(1), 315-326 (1992)
LiOtBu Promoted 5?Exo?dig Cyclization of Propargyl Alcohols and Isocyanates for the Synthesis of Multisubstituted 3H?Oxazol?2?ones and Oxazolidin?2?ones.
Savarimuthu S A, et al.
ChemistrySelect, 1(9), 2035-2039 (2016)
Lithium tert-Butoxide.
Caine D.
e-EROS Encyclopedia of Reagents for Organic Synthesis null
Organoselenium chemistry. 4. Deprotonations with potassium diisopropylamide-lithium tert-butoxide. Alkylation of 1-(phenylseleno) alkenes and bis (phenylseleno) acetals.
Raucher S and Koolpe G A
The Journal of Organic Chemistry, 43(19), 3794-3796 (1978)
Microstructure analysis of poly (lactic acid) obtained by lithium tert-butoxide as initiator.
Kasperczyk J E, et al.
Macromolecules, 28(11), 3937-3939 (1995)
View All Related Papers

Articles

Atomic Layer Deposition of Nanomaterials for Li-Ion Batteries, Fuel Cells, and Solar Cells

Nanomaterials are considered a route to the innovations required for large-scale implementation of renewable energy technologies in society to make our life sustainable.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service