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375195

Sigma-Aldrich

Trimethyltin chloride solution

1.0 M in THF

Synonym(s):

Chlorotrimethylstannane, Chlorotrimethyltin, Trimethylchlorostannane, Trimethylchlorotin, Trimethylstannyl chloride, Trimethyltin chloride

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About This Item

Linear Formula:
(CH3)3SnCl
CAS Number:
1066-45-1
Molecular Weight:
199.27
Beilstein:
3535111
MDL number:
MFCD00000520
UNSPSC Code:
12352103
PubChem Substance ID:
24863371
NACRES:
NA.22

form

liquid

Quality Level

200

concentration

1.0 M in THF

density

0.988 g/mL at 25 °C

SMILES string

C[Sn](C)(C)Cl

InChI

1S/3CH3.ClH.Sn/h3*1H3;1H;/q;;;;+1/p-1

InChI key

KWTSZCJMWHGPOS-UHFFFAOYSA-M

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Packaging

The 25 mL Sure/Seal™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Signal Word

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Respiratory system

Supplementary Hazards

EUH018,EUH019

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

1.4 °F - closed cup

Flash Point(C)

-17 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCQ2575
MKCN1434
SHBK2863
SHBJ6640
SHBH1061V

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Nguyen Quynh Huong et al.
Biological & pharmaceutical bulletin, 34(12), 1856-1863 (2011-12-02)
The organotin trimethyltin (TMT) is well known to cause neuronal degeneration in the hippocampal dentate gyrus of mice. The first purpose of the present study was to examine whether the cyclooxygenase (COX) inhibitor indomethacin could ameliorate neuronal degeneration in the
Ana-Maria Florea et al.
Cell calcium, 37(3), 251-258 (2005-01-27)
Humans are exposed to organotins, like trimethyltin (TMT) chloride via air, water and food, and intoxication might result in severe health complications. Toxic effects of organotin compounds are well documented, but possible mechanisms remain unclear and only little information is
Koichi Kawada et al.
Journal of neuroscience research, 86(7), 1635-1646 (2008-01-10)
Our earlier study demonstrated that in vivo acute treatment with trimethyltin chloride (TMT) produces severe neuronal damage in the dentate gyrus and cognition impairment in mice. In the present study, we assessed whether TMT was capable of causing neuronal degeneration
Guangshu Zhai et al.
Chemosphere, 72(3), 389-399 (2008-04-25)
The photodegradation of methyltins, as environmental pollutants, has scarcely been studied so far because of the shortage of rapid and sensitive speciation methods, even though they have very simple structures. The photodegradation of monomethyltin trichloride (MMT), dimethyltin dichloride (DMT) and
Mengmeng Wang et al.
Toxicology in vitro : an international journal published in association with BIBRA, 22(5), 1136-1142 (2008-04-16)
In this study we intended to evaluate the cytotoxic and genotoxic effects of trimethyltin chloride (TMT), one of the most widely used organometallic compounds, on liver cells with the rat liver epithelial cell line IAR20. The results showed that TMT
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