Skip to Content
MilliporeSigma
All Photos(2)

Key Documents

More Documents

371343

Sigma-Aldrich

4-Hydroxy-TEMPO benzoate, free radical

97%

Synonym(s):

4-Hydroxy-TEMPO benzoate, 4-Hydroxy-2,2,6,6-tetramethylpiperidine 1-oxyl benzoate

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C16H22NO3
CAS Number:
3225-26-1
Molecular Weight:
276.35
Beilstein:
1431263
MDL number:
MFCD00075563
UNSPSC Code:
12352000
PubChem Substance ID:
24863101
NACRES:
NA.22

Assay

97%

form

solid

mp

99-101 °C (lit.)

SMILES string

CC1(C)CC(CC(C)(C)N1[O])OC(=O)c2ccccc2

InChI

1S/C16H22NO3/c1-15(2)10-13(11-16(3,4)17(15)19)20-14(18)12-8-6-5-7-9-12/h5-9,13H,10-11H2,1-4H3

InChI key

MJEDTBDGYVATPI-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

4-Hydroxy-TEMPO benzoate is a 4-substituted 2,2,6,6-tetramethylpiperidyl-1-oxy (TEMPO) derivative.

Application

4-Hydroxy-TEMPO benzoate was employed as spin probe to investigate the mechanism of synthesis of SBA-15 and to evaluate its surface properties and pore structure by electron paramagnetic resonance spectroscopy (EPR). It was also used for the functionalization of various polydienes (polybutadiene and polyisoprene). Functionalized polydienes were analyzed by gel permeation chromatography.
Recycling catalyst in hypochlorite/bromite-nitroxide oxidizing system for conversion of alcohols to aldehydes, ketones, and carboxylic acids. It circumvents the need to use a catalytic or stoichiometric heavy metal oxidant.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 1

1 of 1

3-Carboxy-PROXYL 98%

Sigma-Aldrich

253324

3-Carboxy-PROXYL

Study of the formation of the mesoporous material SBA-15 by EPR spectroscopy.
Ruthstein S, et al.
The Journal of Physical Chemistry B, 107(8), 1739-1748 (2003)
Janske Nel et al.
International journal of pharmaceutics, 554, 87-92 (2018-11-07)
Oxygen is essential in physiology and pathophysiology. Electron paramagnetic resonance (EPR) oximetry, using oxygen sensitive paramagnetic materials, could be attractive for measuring oxygen in tissues. The aim of the present study was to assess the properties of lipid nanocapsules (LNCs)
Controlled ?Grafting-from? of poly [styrene-co-maleic anhydride] onto polydienes using nitroxide chemistry.
Bonilla-Cruz J, et al.
European Polymer Journal, 46(2), 298-312 (2010)
The Journal of Organic Chemistry, 55, 462-462 (1990)
M P Do et al.
International journal of pharmaceutics, 486(1-2), 38-51 (2015-03-21)
Periodontitis is the primary cause of tooth loss in adults and a very wide-spread disease. Recently, composite implants, based on a drug release rate controlling polymer and an adhesive polymer, have been proposed for an efficient local drug treatment. However
View All Related Papers

Articles

TEMPO Catalyzed Oxidations

TEMPO (2,2,6,6-Tetramethylpiperidinyloxy or 2,2,6,6-Tetramethylpiperidine 1-oxyl) and its derivatives are stable nitroxy radicals used as catalysts in organic oxidation reactions. TEMPO was discovered by Lebedev and Kazarnovskii in 1960. The stable free radical nature of TEMPO is due to the presence of bulky substituent groups, which hinder the reaction of the free radical with other molecules.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service