255025

Hexylmagnesium bromide solution

2.0 M in diethyl ether

• Synonym(s): 1-Hexylmagnesium bromide, Bromohexylmagnesium, n-hexylmagnesium bromide
• Linear Formula: CH₃(CH₂)₅MgBr
• CAS Number: 3761-92-0
• Molecular Weight: 189.38
• Beilstein: 3535624
• MDL number: MFCD00000046
• UNSPSC Code: 12352103
• PubChem Substance ID: 24855279
• NACRES: NA.22

Properties

• reaction suitability: reaction type: Grignard Reaction
• concentration: 2.0 M in diethyl ether
• density: 0.965 g/mL at 25 °C
• SMILES string: CCCCCC[Mg]Br
• InChI: 1S/C6H13.BrH.Mg/c1-3-5-6-4-2;;/h1,3-6H2,2H3;1H;/q;;+1/p-1
• InChI key: SFXUWNMDTWQSHE-UHFFFAOYSA-M

Description

General description

Hexylmagnesium bromide, also known as n-hexylmagnesium bromide, is a useful organomagnesium compound that is commonly used in organic synthesis. It is typically prepared by reacting magnesium turnings with 1-bromohexane in diethyl ether solvent.

Application

Hexylmagnesium bromide solution can be used as a reagent in addition reactions. It can add to various electrophiles, such as carbonyl compounds, to form alcohols or carboxylic acids. These types of reactions are commonly used for the synthesis of pharmaceuticals, natural products, and other organic compounds. It is also used to reduce certain functional groups, such as ketones, esters, and nitriles, to form alcohols or amines.

Safety Information

• Pictograms: GHS02,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H260,H302,H314,H336
• Precautionary Statements: P210 - P231 + P232 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3 - Water-react 1
• Target Organs: Central nervous system
• Supplementary Hazards: EUH019
• Storage Class Code: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• WGK: WGK 3
• Flash Point(F): -40.0 °F - closed cup
• Flash Point(C): -40 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves