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215686

Sigma-Aldrich

Disperse Yellow 3

Dye content 30 %

Synonym(s):

4-(2-Hydroxy-5-methylphenylazo)acetanilide, N-[4-(2-Hydroxy-5-methylphenylazo)phenyl]acetamide

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About This Item

Empirical Formula (Hill Notation):
C15H15N3O2
CAS Number:
Molecular Weight:
269.30
Colour Index Number:
11855
Beilstein:
1915225
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

form

powder

Quality Level

composition

Dye content, 30%

mp

268-270 °C (lit.)

λmax

357 nm

ε (extinction coefficient)

≥6500 at 354-360 nm in ethanol and water at 0.02 g/L

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

CC(=O)Nc1ccc(cc1)N=Nc2cc(C)ccc2O

InChI

1S/C15H15N3O2/c1-10-3-8-15(20)14(9-10)18-17-13-6-4-12(5-7-13)16-11(2)19/h3-9,20H,1-2H3,(H,16,19)

InChI key

PXOZAFXVEWKXED-UHFFFAOYSA-N

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General description

Disperse Yellow 3 [2-(4′-acetamidophenylazo)-4-methylphenol] (DY3) belongs to the class of monoazo (heterocyclic) dyes. It is carcinogenic in nature.

Biochem/physiol Actions

Disperse Yellow 3 has been used to study its degradation process by P. ostreatus using reversed phase high performance liquid chromatography (HPLC) and UV–visible spectrophotometry.

Pictograms

Exclamation markHealth hazard

Signal Word

Warning

Hazard Statements

Hazard Classifications

Carc. 2 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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L. Kanerva, P. Elsner, J.E. Wahlberg, H.I. Maibach
Handbook of Occupational Dermatology (2013)
HPLC and spectrophotometric analysis of biodegradation of azo dyes by Pleurotus ostreatus
Zhao X
Dyes and Pigments, 73, 322-325 (2007)
Peroxidase-Catalyzed Oxidation of Azo Dyes: Mechanism of Disperse Yellow 3 Degradation
Spadaro J.T and Renganathan V
Archives of Biochemistry and Biophysics, 312, 301-307 (1994)
J T Spadaro et al.
Archives of biochemistry and biophysics, 312(1), 301-307 (1994-07-01)
Disperse Yellow 3 [2-(4'-acetamidophenylazo)-4-methylphenol] (DY3) (I) is an important yellow dye used in industry and is also a carcinogen. Earlier we demonstrated that lignin-degrading cultures of white-rot basidiomycete Phanerochaete chrysosporium degrade DY3 to CO2. In this report, we have examined
P S Gray et al.
Cytobios, 25(99-100), 175-182 (1979-01-01)
Azo dyes have been shown to be mutagenic and toxic in a variety of organisms. The azo dye, Dispersion Yellow 3 is a pollutant in the river water supply of Northern Georgia. Preliminary and definitive studies have indicated that it

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