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Triethylenetetramine tetrahydrochloride

Name: Triethylenetetramine tetrahydrochloride
Brand: ALDRICH

97%

Synonym(s):

Cuprior, Trientine tetrahydrochloride

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About This Item

Linear Formula:

NH₂CH₂CH₂(NHCH₂CH₂)₂NH₂· 4HCl

CAS Number:

4961-40-4

Molecular Weight:

292.08

EC Number:

225-604-3

MDL number:

MFCD00012890

UNSPSC Code:

12352100

PubChem Substance ID:

24849963

NACRES:

NA.22

Assay

97%

mp

269-270 °C (lit.)

SMILES string

Cl.Cl.Cl.Cl.NCCNCCNCCN

InChI

1S/C6H18N4.4ClH/c7-1-3-9-5-6-10-4-2-8;;;;/h9-10H,1-8H2;4*1H

InChI key

OKHMDSCYUWAQPT-UHFFFAOYSA-N

Related Categories

Organic Building Blocks

General description

Triethylenetetramine tetrahydrochloride is a copper-chelating agent

Application

Triethylenetetramine tetrahydrochloride was used as primary amine displacer in affinity chromatography.

Biochem/physiol Actions

Triethylenetetramine tetrahydrochloride induces apoptosis of acinar cells of the pancreas in male Fischer 344 rats.

Pictograms

GHS08,GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335,H351

Precautionary Statements

P201 - P302 + P352 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Apoptosis of acinar cells in the pancreas of rats fed on a copper-depleted diet.

S Kishimoto et al.

Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 45(8), 489-495 (1994-04-01)

Male Fischer 344 rats weighing 80-90 g were fed on a copper-depleted diet supplemented with 0.6% triethylenetetramine tetrahydrochloride (a copper chelator), and the death of pancreatic acinar cells of these rats was investigated morphologically and biochemically. The weight of the

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