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143936

Sigma-Aldrich

Propionamide

97%

Synonym(s):

Propanamide, Propylamide

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About This Item

Linear Formula:
CH3CH2CONH2
CAS Number:
Molecular Weight:
73.09
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

bp

213 °C (lit.)

mp

76-79 °C (lit.)

solubility

alcohol: freely soluble
chloroform: freely soluble
diethyl ether: freely soluble
water: freely soluble

density

1.042 g/mL at 25 °C (lit.)

functional group

amide

SMILES string

CCC(N)=O

InChI

1S/C3H7NO/c1-2-3(4)5/h2H2,1H3,(H2,4,5)

InChI key

QLNJFJADRCOGBJ-UHFFFAOYSA-N

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General description

Propionamide on γ-irradiation reacts with sulfur dioxide and this reaction has been studied by ESR spectroscopy, gas absorption measurements and X-ray diffraction.

Application

Propionamide was used as adsorbent in the determination of adsorption isotherms of acetamide and propionamide on multi-wall carbon nanotube. It was used in a robust screening method to study biotransformations using (+)-γ-lactamase enzyme.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Reactions of Gases with Irradiated Organic Solids: III. Reactions of Propionamide, n-Butyramide, Isobutyramide, Methacrylamide, Valeramide, and Stearamide with Sulfur Dioxide.
Perotti A, et al.
Mol. Cryst. Liq. Cryst., 9(1), 323-342 (2969)
Ramesh Narayanan et al.
Molecular endocrinology (Baltimore, Md.), 22(11), 2448-2465 (2008-09-20)
Androgen receptor (AR) ligands are important for the development and function of several tissues and organs. However, the poor oral bioavailability, pharmacokinetic properties, and receptor cross-reactivity of testosterone, coupled with side effects, place limits on its clinical use. Selective AR
J D Stone et al.
Toxicology and applied pharmacology, 161(1), 50-58 (1999-11-24)
Neurofilament modification and accumulation, occurring in toxicant-induced neuropathies, has been proposed to compromise fast axonal transport and contribute to neurological symptoms or pathology. The current study compares the effects of the neurotoxicants acrylamide (ACR) and 2,5-hexanedione (2,5-HD) on the quantity
Study of Adsorption Isotherms of Acetamide and Propionamide on Carbon Nanotube.
Vadi M and Moradi N.
Orient. J. Chem., 27(4), 1491-1491 (2011)
Dale W Sickles et al.
Toxicology and applied pharmacology, 222(1), 111-121 (2007-06-02)
The microtubule (MT) motor protein kinesin is a vital component of cells and organs expressing acrylamide (ACR) toxicity. As a mechanism of its potential carcinogenicity, we determined whether kinesins involved in cell division are inhibited by ACR similar to neuronal

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