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About This Item
Linear Formula:
FC6H4COCl
CAS Number:
Molecular Weight:
158.56
Beilstein:
636864
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Assay
99%
refractive index
n20/D 1.536 (lit.)
bp
90-92 °C/15 mmHg (lit.)
mp
4 °C (lit.)
density
1.328 g/mL at 25 °C (lit.)
functional group
acyl chloride
SMILES string
Fc1ccccc1C(Cl)=O
InChI
1S/C7H4ClFO/c8-7(10)5-3-1-2-4-6(5)9/h1-4H
InChI key
RAAGZOYMEQDCTD-UHFFFAOYSA-N
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General description
2-Fluorobenzoyl chloride reacts with ethyl 5-amino-1-methylpyrazole-4-carboxylate to give N-mono-N,N-di-substituted intermediate which on ring closure yields heteroannulated oxazinone.
Application
2-Fluorobenzoyl chloride has been used in the preparation of 3-(N-Hydroxycarbamimidoyl)-benzoic acid methyl ester. It has been used to develop an hollow-fiber liquid phase microextraction with in situ derivatization method coupled with HPLC-UV for the determination of metformin hydrochloride in biological fluids.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 3
Flash Point(F)
251.6 °F - closed cup
Flash Point(C)
122 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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