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RAD51C

RAD51 paralog C

Synonyms:
BROVCA3, FANCO, R51H3, RAD51L2
Species:
UniProtKB ID:
Gene ID:
  • Human(5889) Summary: This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
  • Mouse(114714) RAD51 homolog C
  • Rat(497976) RAD51 paralog C
  • cow(540886) RAD51 paralog C
  • sheep(101106090) RAD51 homolog C (S. cerevisiae)
  • naked mole-rat(101714867) RAD51 homolog C (S. cerevisiae)
  • Domestic Rabbit(100339674) RAD51 homolog C (S. cerevisiae)
  • domestic guinea pig(100727310) RAD51 homolog C (S. cerevisiae)
  • fruit fly(35937) CG2412 gene product from transcript CG2412-RB
  • dog(480573) RAD51 homolog C (S. cerevisiae)
  • Horse(100070966) RAD51 homolog C (S. cerevisiae)
  • domestic cat(101096020) RAD51 homolog C (S. cerevisiae)
  • chicken(417626) RAD51 homolog C (S. cerevisiae)
  • Thale Cress(819136) DNA repair protein RAD51 homolog 3
  • Zebrafish(450081) rad51 homolog C (S. cerevisiae)

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-RAD51C antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-RAD51C antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-RAD51C antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Rad51c,
Species
mouse
MISSION® esiRNA, targeting human RAD51C,
Species
human