Meloxicam decreases the migration and invasion of CF41.Mg canine mammary carcinoma cells.

Meloxicam decreases the migration and invasion of CF41.Mg canine mammary carcinoma cells.

Oncology letters (2017-08-07)

María P Iturriaga, Rodolfo Paredes, Jose I Arias, Cristian G Torres

RESUMO

Cyclooxygenase (COX)-2 expression is positively correlated with malignant features in canine mammary carcinomas. Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit COX activity and may therefore possess anticancer effects. Meloxicam is an NSAID that is widely used in human and veterinary medicine. High concentrations of meloxicam have been reported to be antitumorigenic

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A9917

Sigma-Aldrich

Anti-Mouse IgG (Fab specific)–Peroxidase antibody produced in goat, affinity isolated antibody, buffered aqueous solution

A6667

Sigma-Aldrich

Anti-Rabbit IgG (whole molecule), F(ab′)₂ fragment−Peroxidase antibody produced in goat, affinity isolated antibody, buffered aqueous solution