- Synthesis of trisubstituted alkenes via olefin cross-metathesis.
Synthesis of trisubstituted alkenes via olefin cross-metathesis.
Organic letters (2000-06-03)
A K Chatterjee, R H Grubbs
PMID10836036
RESUMO
[formula: see text] Trisubstituted alkenes have been prepared for the first time via intermolecular olefin cross-metathesis, using 1,3-dimesityl-4,5-dihydroimidazol-2-ylidene ruthenium alkylidene complexes 3a,b in good yields with moderate E selectivity. In addition, protected alcohols near the geminal disubstituted olefin improve reactivity for cross-metathesis.