Novel 6,12-disubstituted chrysene as potent anticancer agent: synthesis, in vitro and in vivo study.

Novel 6,12-disubstituted chrysene as potent anticancer agent: synthesis, in vitro and in vivo study.

European journal of medicinal chemistry (2010-08-13)

Bimal K Banik, Frederick F Becker

RESUMO

We describe herein the synthesis of novel 6,12-distributed chrysene as potent anticancer agents. In vitro and in vivo studies are also reported here.

MATERIAIS

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Supelco

Chrysene, analytical standard

Supelco

Chrysene, certified reference material, TraceCERT^®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Chrysene, BCR^®, certified reference material