GW21470

Anti-PPFIA1 (ab1) antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

• Sinônimo(s): Anti-LAR-interacting protein 1, Anti-LIP.1, Anti-LIP1, Anti-LIPA1_HUMAN, Anti-LIPRIN, Anti-Liprin-α-1
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: chicken
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• reatividade de espécies: rat, mouse, human
• fabricante/nome comercial: Genway 15-288-21470
• técnica(s): western blot: suitable
• nº de adesão NCBI: NP_003617.1
• nº de adesão UniProt: Q13136
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... PPFIA1(8500)

Descrição

Imunogênio

Immunogen Sequence: GI # 4505983, sequence 310-360

Recombinant PTPRF interacting protein α 1 isoform b

Aplicação

Anti-PPFIA1 (ab1) antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Ações bioquímicas/fisiológicas

Liprin-α-1 is a cytoplasmic 160kDa phosphoserine protein encoded by the PPFIA1 gene in humans. It encodes liprin α, a protein involved in cell adhesion, integrin expression and cell-matrix interactions. PPFIA1 may act as a potential functional candidate for acute lung injury risk gene for future research. It is frequently co-amplified with the Cyclin D1 gene in oral carcinomas and may present a biomarker as well as a novel target for specific gene therapy. Liprin′s function is to localize LAR family tyrosine phosphatases at specific sites on the plasma membrane. It may help in regulating their interaction with the extracellular environment and their associations with substrates. PPFIA1 may regulate the disassembly of focal adhesions and help to orchestrate cell-matrix interactions.

forma física

Solution in phosphate buffered saline containing 0.02% sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)