8.52229

Fmoc-Thr(Ac₃AcNH-α-Gal)-OH

Novabiochem^®

• Sinônimo(s): Fmoc-Thr(Ac₃AcNH-α-Gal)-OH, N-α-Fmoc-O-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-α-D-galactopyranosyl)-L-threonine
• Fórmula empírica (Notação de Hill): C₃₃H₃₈N₂O₁₃
• Número CAS: 116783-35-8
• Peso molecular: 670.66
• Número MDL: MFCD00171374
• Código UNSPSC: 12352209

Propriedades

• Nível de qualidade: 200
• linha de produto: Novabiochem^®
• Ensaio: ≥95% (TLC); ≥95.0% (HPLC)
• forma: powder
• adequação da reação: reaction type: Fmoc solid-phase peptide synthesis
• fabricante/nome comercial: Novabiochem^®
• aplicação(ões): peptide synthesis
• grupo funcional: Fmoc
• temperatura de armazenamento: 15-25°C
• InChI: 1S/C33H38N2O13/c1-16(27(31(40)41)35-33(42)44-14-25-23-12-8-6-10-21(23)22-11-7-9-13-24(22)25)45-32-28(34-17(2)36)30(47-20(5)39)29(46-19(4)38)26(48-32)15-43-18(3)37/h6-13,16,25-30,32H,14-15H2,1-5H3,(H,34,36)(H,35,42)(H,40,41)/t16-,26-,27+,28-,29+,30-,32+/m1/s1
• chave InChI: OXLCJWGAUPPZQJ-ZNHCDWFHSA-N

Descrição

Descrição geral

The O-glycosidic linkage and the O-acetyl protection in this building block is stable to both piperidine and TFA ^[1], making it completely compatible with standard protocols in Fmoc solid phase peptide synthesis. Removal of the acetyl protecting groups is best carried out by treatment of the peptidyl resin with methanolic ammonia prior to cleavage.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Fmoc SPPS of Peptides containing Post-Translational Modifications

Literature references

^[1] J. Kihlberg in ′Fmoc solid phase peptide synthesis: a practical approach′, W.C. Chan & P.D. White (Eds.), Oxford University Press, Oxford, 2000, pp. 195.

Ligação

Replaces: 04-12-8104

Nota de análise

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA2)): ≥ 95 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Identity (NMR, 1H): passes test
Identity (NMR): passes test
NMR-spectrum: passes test

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Informações legais

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable