STAT5A
signal transducer and activator of transcription 5A
Sinônimos:
MGF, STAT5
Espécies:
Human STAT5A (6776), Mouse Stat5a (20850), Rat Stat5a (24918), dog STAT5A (490968), Horse STAT5A (100052904), domestic cat STAT5A (101090913), cow STAT5A (282375), sheep STAT5A (443419), naked mole-rat Stat5a (101723770), domestic guinea pig Stat5a (100716811)
ID UniProtKB:
ID do gene:
- Human(6776) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq, Jul 2008]
- Mouse(20850) signal transducer and activator of transcription 5A
- Rat(24918) signal transducer and activator of transcription 5A
- dog(490968) signal transducer and activator of transcription 5A
- Horse(100052904) signal transducer and activator of transcription 5A
- domestic cat(101090913) signal transducer and activator of transcription 5A
- cow(282375) signal transducer and activator of transcription 5A
- sheep(443419) signal transducer and activator of transcription 5A
- naked mole-rat(101723770) signal transducer and activator of transcription 5A
- domestic guinea pig(100716811) signal transducer and activator of transcription 5A
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ELISA
Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-phospho-STAT5A/B (Tyr694/699) Antibody, clone 8-5-2, clone 8-5-2, Upstate®, from mouse,
Reatividade de espécies
bovine, human, mouse, rat, sheep
Aplicação
western blot
Anti-STAT5A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Anti-phospho-STAT5A/B (Tyr694/699) Antibody, clone A11W, rabbit monoclonal, culture supernatant, clone A11W, from rabbit,
Reatividade de espécies
bovine, chimpanzee, human, mouse, rat
Aplicação
western blot
Anti-STAT5A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Anti-phospho-STAT5A/B (Ser726/Ser731) Antibody, serum, Upstate®,
Reatividade de espécies
human, mouse, rat
Aplicação
western blot
Proteins
Número do produto
Descrição
Espécies
STAT5, His tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espécies
human