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Merck

SPAG6

sperm associated antigen 6

Sinônimos:
Repro-SA-1, pf16
Espécies:
ID UniProtKB:
ID do gene:
  • Human(9576) Summary: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
  • Mouse(50525) sperm associated antigen 6
  • Rat(360747) sperm associated antigen 6
  • Zebrafish(431757) sperm associated antigen 6
  • dog(477978) sperm associated antigen 6
  • domestic cat(101096155) sperm associated antigen 6
  • chicken(420505) sperm associated antigen 6
  • domestic guinea pig(100724896) sperm associated antigen 6
  • naked mole-rat(101729190) sperm associated antigen 6
  • cow(539424) sperm associated antigen 6
  • sheep(101103745) sperm associated antigen 6

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-SPAG6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
Anti-SPAG6 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
bovine, dog, horse, human, mouse, pig, rabbit, rat
Aplicação
western blot
Monoclonal Anti-SPAG6 antibody produced in mouse, clone 2F3, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
Anti-SPAG6 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot
Monoclonal Anti-SPAG6 antibody produced in mouse, clone 3E3, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
western blot

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human SPAG6,
Espécies
human