SNCA
synuclein, alpha (non A4 component of amyloid precursor)
NACP, PARK1, PARK4, PD1
Human SNCA (6622), Mouse Snca (20617), Rat Snca (29219), chicken SNCA (395393), Horse SNCA (100053270), domestic cat SNCA (101091694), dog SNCA (478478), cow SNCA (282857), sheep SNCA (100294604), domestic guinea pig Snca (100725375)
- Human(6622) Summary: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009]
- Mouse(20617) synuclein, alpha
- Rat(29219) synuclein, alpha (non A4 component of amyloid precursor)
- chicken(395393) synuclein, alpha (non A4 component of amyloid precursor)
- Horse(100053270) synuclein, alpha (non A4 component of amyloid precursor)
- domestic cat(101091694) synuclein, alpha (non A4 component of amyloid precursor)
- dog(478478) synuclein, alpha (non A4 component of amyloid precursor)
- cow(282857) synuclein, alpha (non A4 component of amyloid precursor)
- sheep(100294604) synuclein, alpha (non A4 component of amyloid precursor)
- domestic guinea pig(100725375) synuclein, alpha (non A4 component of amyloid precursor)
- naked mole-rat(101700039) synuclein, alpha (non A4 component of amyloid precursor)
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Antibodies
Anti-phospho-α-synuclein (Ser129) Antibody, clone PS129, ,
bovine, human, mouse, porcine, rat
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Aggregated a-Synuclein Antibody, clone 5G4, clone 5G4, from mouse, purified by affinity chromatography,
human
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-α-Synuclein (Ser129) Antibody, clone 81A, clone 81A, from mouse,
human, mouse
electron microscopy
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
Anti-α-Synuclein antibody, Mouse monoclonal, clone Syn211, purified from hybridoma cell culture,
human, zebra finch
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-α-Synuclein Antibody, clone Syn211, ascites fluid, clone Syn211, Upstate®,
human
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Proteins
α-Synuclein human, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder,
human
α-Synuclein A53T human, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder,
human
α-Synuclein E46K human, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder,
human