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Merck

PDHB

pyruvate dehydrogenase (lipoamide) beta

Sinônimos:
PDHBD, PDHE1-B, PHE1B
Espécies:
ID UniProtKB:
ID do gene:
  • Human(5162) Summary: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012]
  • Mouse(68263) pyruvate dehydrogenase (lipoamide) beta
  • Rat(289950) pyruvate dehydrogenase (lipoamide) beta
  • cow(613610) pyruvate dehydrogenase (lipoamide) beta
  • sheep(101121975) pyruvate dehydrogenase (lipoamide) beta
  • domestic guinea pig(100733476) pyruvate dehydrogenase (lipoamide) beta
  • naked mole-rat(101714134) pyruvate dehydrogenase (lipoamide) beta
  • Zebrafish(406428) pyruvate dehydrogenase (lipoamide) beta
  • Horse(100050581) pyruvate dehydrogenase (lipoamide) beta
  • domestic cat(101100374) pyruvate dehydrogenase (lipoamide) beta
  • dog(476574) pyruvate dehydrogenase (lipoamide) beta
  • chicken(416066) pyruvate dehydrogenase (lipoamide) beta

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-PDHB antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicação
immunohistochemistry
western blot
Anti-PDHB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-PDHB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
Monoclonal Anti-PDHB antibody produced in mouse, clone 1D1, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
Anti-PDHB antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot

Kits

Número do produto
Descrição
Espécies
Pyruvate Dehydrogenase Activity Assay Kit, sufficient for 100 colorimetric tests,
Espécies
rat, mouse, human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human PDHB,
Espécies
human
MISSION® esiRNA, targeting mouse Pdhb,
Espécies
mouse