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Merck

NF2

neurofibromin 2 (merlin)

Sinônimos:
ACN, BANF, SCH
Espécies:
ID UniProtKB:
ID do gene:
  • Human(4771) Summary: This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. [provided by RefSeq, Jul 2008]
  • Mouse(18016) neurofibromatosis 2
  • Rat(25744) neurofibromin 2 (merlin)
  • chicken(395158) neurofibromin 2 (bilateral acoustic neuroma)
  • dog(477535) neurofibromin 2 (merlin)
  • domestic cat(101087787) neurofibromin 2 (merlin)
  • cow(540479) neurofibromin 2 (merlin)
  • Horse(100058977) neurofibromin 2 (merlin)
  • Domestic Rabbit(100357691) neurofibromin 2 (merlin)
  • naked mole-rat(101706100) neurofibromin 2 (merlin)
  • domestic guinea pig(100715365) neurofibromin 2 (merlin)
  • sheep(101107995) neurofibromin 2 (merlin)

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-NF2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human, mouse, rat
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-NF2 antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot
Anti-phospho-Merlin (pSer10) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunohistochemistry

western blot
ANTI-MERLIN(N-TERMINAL) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti- NF2 antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human NF2,
Espécies
human