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IL21R

interleukin 21 receptor

Sinônimos:
CD360, NILR
Espécies:
ID UniProtKB:
ID do gene:
  • Human(50615) Summary: The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
  • Mouse(60504) interleukin 21 receptor
  • Rat(308977) interleukin 21 receptor
  • Zebrafish(100134976) interleukin 21 receptor
  • cow(617967) interleukin 21 receptor
  • Horse(100066814) interleukin 21 receptor
  • domestic cat(101096026) interleukin 21 receptor
  • dog(608011) interleukin 21 receptor
  • chicken(416586) interleukin 21 receptor
  • domestic guinea pig(100721842) interleukin 21 receptor
  • naked mole-rat(101701307) interleukin 21 receptor
  • sheep(100820753) interleukin 21 receptor

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ELISA

Número do produto
Descrição
Espécies
Human IL21R / Interleukin-21 Receptor ELISA Kit, ,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-IL-21 Receptor (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunofluorescence

western blot
Anti-IL21R antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human IL21R,
Espécies
human