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Merck

DCTN2

dynactin 2 (p50)

Sinônimos:
DCTN50, DYNAMITIN, RBP50
Espécies:
ID UniProtKB:
ID do gene:
  • Human(10540) Summary: This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2012]
  • Mouse(69654) dynactin 2
  • Rat(299850) dynactin 2 (p50)
  • Zebrafish(394141) dynactin 2 (p50)
  • cow(527201) dynactin 2 (p50)
  • Horse(100050464) dynactin 2 (p50)
  • domestic cat(101093950) dynactin 2 (p50)
  • dog(474415) dynactin 2 (p50)
  • chicken(395587) dynactin 2 (p50)
  • naked mole-rat(101713049) dynactin 2 (p50)
  • domestic guinea pig(100721002) dynactin 2 (p50)
  • sheep(101119807) dynactin 2 (p50)
  • Domestic Rabbit(100339187) dynactin 2 (p50)

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-DCTN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot
Anti-DCTN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human, mouse, rat
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-DCTN2 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicação
western blot
Monoclonal Anti-DCTN2 antibody produced in mouse, clone 2G7, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
immunofluorescence

western blot

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human DCTN2,
Espécies
human
MISSION® esiRNA, targeting mouse Dctn2,
Espécies
mouse